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Put two or three cybersecurity products side by side and see how they differ on deployment, pricing, features, integrations and compliance.

Microsoft Defender for Office 365Proofpoint Targeted Attack Protection2 of 3 products
Microsoft logo

Microsoft Defender for Office 365

by Microsoft

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Proofpoint logo

Proofpoint Targeted Attack Protection

by Proofpoint

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Overview

What it is

Microsoft Defender for Office 365

Microsoft Defender for Office 365 from Microsoft focuses on malware prevention. Key capabilities: Safe Links. Compare it with the leading Email Security alternatives.

Proofpoint Targeted Attack Protection

Shortlisting Threat Detection tools? Proofpoint Targeted Attack Protection by Proofpoint brings VAP identification, with cloud deployment. See strengths and alternatives.

Product type

Microsoft Defender for Office 365

Email Security / Collaboration Security

Proofpoint Targeted Attack Protection

Advanced Threat Detection & URL/Attachment Sandboxing Engine

Best for

Microsoft Defender for Office 365

Cross-industry

Proofpoint Targeted Attack Protection

Enterprise, Banking, Defense, Healthcare, Government

Pricing

Pricing model

Microsoft Defender for Office 365

Contact Vendor

Proofpoint Targeted Attack Protection

Contact Vendor

Free trial

Microsoft Defender for Office 365

Free trial: yes

Proofpoint Targeted Attack Protection

Free trial: yes

Deployment

Deployment options

Microsoft Defender for Office 365

Cloud

Proofpoint Targeted Attack Protection

SaaSCloud

Deployment details

Microsoft Defender for Office 365

Cloud; Microsoft 365 cloud

Proofpoint Targeted Attack Protection

Cloud (SaaS); Cloud-native SaaS

Data residency

Microsoft Defender for Office 365

Microsoft 365 tenant region/service dependent

Proofpoint Targeted Attack Protection

US; EU; Global cloud

Key features

What it offers

Microsoft Defender for Office 365

  • Anti-phishing
  • Safe Links
  • Safe Attachments
  • BEC protection
  • Threat investigation
  • Automated response
  • Email security
  • Malware prevention

Proofpoint Targeted Attack Protection

  • URL Defense click-time analysis
  • Attachment Defense sandbox
  • VAP identification
  • Supplier risk insights
  • Threat actor attribution
  • Weaponized URL blocking
  • Zero-day attachment sandboxing
  • VAP threat monitoring

Platform & access

API access

Microsoft Defender for Office 365

API access: yes

Proofpoint Targeted Attack Protection

API access: yes

Single sign-on (SSO)

Microsoft Defender for Office 365

SSO: yes

Proofpoint Targeted Attack Protection

SSO: yes

Role-based access (RBAC)

Microsoft Defender for Office 365

RBAC: yes

Proofpoint Targeted Attack Protection

RBAC: yes

Multi-tenant

Microsoft Defender for Office 365

Multi-tenant: yes

Proofpoint Targeted Attack Protection

Multi-tenant: yes

Mobile app

Microsoft Defender for Office 365

Mobile app: no

Proofpoint Targeted Attack Protection

Mobile app: no

Supported platforms

Microsoft Defender for Office 365

Microsoft 365Exchange OnlineSharePointOneDriveTeams

Proofpoint Targeted Attack Protection

CloudMicrosoft 365Google Workspace

Compliance

Microsoft Defender for Office 365

Microsoft 365 compliance portfolio

Proofpoint Targeted Attack Protection

SOC 2 Type IIISO 27001GDPRHIPAAFedRAMP Authorized

Integrations & coverage

Integrations

Microsoft Defender for Office 365

Microsoft 365Microsoft Defender XDRMicrosoft EntraMicrosoft Purview

Proofpoint Targeted Attack Protection

Microsoft 365Google WorkspaceCrowdStrikePalo AltoSplunkSentinel

Industries

Microsoft Defender for Office 365

Cross-industry

Proofpoint Targeted Attack Protection

EnterpriseBankingDefenseHealthcareGovernment

Regions

Microsoft Defender for Office 365

Global

Proofpoint Targeted Attack Protection

GlobalNorth AmericaEuropeAsia-Pacific

Vendor

Company

Microsoft Defender for Office 365

Microsoft

Proofpoint Targeted Attack Protection

Proofpoint

Headquarters

Microsoft Defender for Office 365

Redmond, Washington, USA

Proofpoint Targeted Attack Protection

Sunnyvale, California, USA

Company size

Microsoft Defender for Office 365

200,000+

Proofpoint Targeted Attack Protection

4,000+

Founded

Microsoft Defender for Office 365

1975

Proofpoint Targeted Attack Protection

2002

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