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Put two or three cybersecurity products side by side and see how they differ on deployment, pricing, features, integrations and compliance.

Microsoft Defender for Office 365Proofpoint Email Protection2 of 3 products
Microsoft logo

Microsoft Defender for Office 365

by Microsoft

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Proofpoint logo

Proofpoint Email Protection

by Proofpoint

View product

Overview

What it is

Microsoft Defender for Office 365

Microsoft Defender for Office 365 from Microsoft focuses on malware prevention. Key capabilities: Safe Links. Compare it with the leading Email Security alternatives.

Proofpoint Email Protection

Get the facts on Proofpoint Email Protection: outbound DLP. Built for inbound malware and spam filtering. Compare it with other Email Security options before you decide.

Product type

Microsoft Defender for Office 365

Email Security / Collaboration Security

Proofpoint Email Protection

Secure Email Gateway & Advanced Threat Defense Platform

Best for

Microsoft Defender for Office 365

Cross-industry

Proofpoint Email Protection

Enterprise, Financial Services, Healthcare, Government, Cross-industry

Pricing

Pricing model

Microsoft Defender for Office 365

Contact Vendor

Proofpoint Email Protection

Contact Vendor

Free trial

Microsoft Defender for Office 365

Free trial: yes

Proofpoint Email Protection

Free trial: yes

Deployment

Deployment options

Microsoft Defender for Office 365

Cloud

Proofpoint Email Protection

SaaSCloudHybrid

Deployment details

Microsoft Defender for Office 365

Cloud; Microsoft 365 cloud

Proofpoint Email Protection

Cloud (SaaS); Hybrid; Cloud-native SaaS; Hybrid gateway

Data residency

Microsoft Defender for Office 365

Microsoft 365 tenant region/service dependent

Proofpoint Email Protection

US; EU; UK; Global cloud

Key features

What it offers

Microsoft Defender for Office 365

  • Anti-phishing
  • Safe Links
  • Safe Attachments
  • BEC protection
  • Threat investigation
  • Automated response
  • Email security
  • Malware prevention

Proofpoint Email Protection

  • Nexus multi-layered filtering
  • Email authentication (DMARC/DKIM/SPF)
  • Dynamic reputation defense
  • Outbound DLP
  • Quarantine management
  • Inbound malware and spam filtering
  • Email spoofing prevention
  • Outbound message policy enforcement

Platform & access

API access

Microsoft Defender for Office 365

API access: yes

Proofpoint Email Protection

API access: yes

Single sign-on (SSO)

Microsoft Defender for Office 365

SSO: yes

Proofpoint Email Protection

SSO: yes

Role-based access (RBAC)

Microsoft Defender for Office 365

RBAC: yes

Proofpoint Email Protection

RBAC: yes

Multi-tenant

Microsoft Defender for Office 365

Multi-tenant: yes

Proofpoint Email Protection

Multi-tenant: yes

Mobile app

Microsoft Defender for Office 365

Mobile app: no

Proofpoint Email Protection

Mobile app: yes

Supported platforms

Microsoft Defender for Office 365

Microsoft 365Exchange OnlineSharePointOneDriveTeams

Proofpoint Email Protection

CloudHybrid ExchangeGoogle Workspace

Compliance

Microsoft Defender for Office 365

Microsoft 365 compliance portfolio

Proofpoint Email Protection

SOC 2 Type IIISO 27001FedRAMP AuthorizedGDPRHIPAA

Integrations & coverage

Integrations

Microsoft Defender for Office 365

Microsoft 365Microsoft Defender XDRMicrosoft EntraMicrosoft Purview

Proofpoint Email Protection

Microsoft 365Google WorkspaceProofpoint TAPSplunkCrowdStrike

Industries

Microsoft Defender for Office 365

Cross-industry

Proofpoint Email Protection

EnterpriseFinancial ServicesHealthcareGovernmentCross-industry

Regions

Microsoft Defender for Office 365

Global

Proofpoint Email Protection

GlobalNorth AmericaEuropeAsia-PacificLatin America

Vendor

Company

Microsoft Defender for Office 365

Microsoft

Proofpoint Email Protection

Proofpoint

Headquarters

Microsoft Defender for Office 365

Redmond, Washington, USA

Proofpoint Email Protection

Sunnyvale, California, USA

Company size

Microsoft Defender for Office 365

200,000+

Proofpoint Email Protection

4,000+

Founded

Microsoft Defender for Office 365

1975

Proofpoint Email Protection

2002

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